???? ???? ?????? ??? ??? ???? ????? ??????? ???? ???? ?????? ?? ??? ???????? ??? ?? ???? ??? ??? ???? ???????.?? ???? ??????? ????? ??? ?????? ?????? ??????? ??????No accumulation of misoprostol acid was observed in various dose research; plasma steady point out was attained within just two times.???? ?? ???? ?????? ???? ???? ?? ?????? ??? ?????? ?